2022 年 41 巻 2 号 p. 35-42
Oral candidiasis has a variety of symptoms and is difficult to diagnose. For example, Erythematous candidiasis is easily misdiagnosed as inflammation, and even Candida-related diseases tend to be intractable if treated without considering the involvement of Candida. Therefore, I wrote a review on oral candidiasis and treatment based on my long time clinical experience and on scientific evidence.
Since Candida is a resident oral microorganism, it is difficult to completely eradicate it. However, if colonizing and invasive forms of Candida pseudohyphae are eradicated, the passing forms of yeast forms of Candida do not remain locally in the oral cavity due to the antibacterial action such as the self-cleansing action of saliva, so the symptoms are improved. The aim and goal of antifungal therapy is to eliminate Candida hyphae by antifungal agents to leave only Candida yeast.