ORAL THERAPEUTICS AND PHARMACOLOGY
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
A Case of secondary thrombocytopenic purpura induced by antibiotic
MASAHIKO HONDAMITSUHIKO MATSUMOTOSEIICHIROU SAITOMITSUYO SHINOHARATADANOBU SEKIWAMASAMICHI ONOMASAAKI TERAKADOHIROSHI SATO
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1992 Volume 11 Issue 2 Pages 62-67

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Abstract
Secondary thrombocytopenia was defined as a decrease in the platelet count to less than 3×104 mm3 and it was induced by Latamoxef (LMOX) administration. A 21 year-old male received a segmental resection of the mandible and a reconstructive surgery due to the calcifying odontogenic cyst. The patient was given totally 23 g of LMOX during 8 days after operation, which was intravenous administrated 2 to 3 g per day. The platelet cout was markedly decreased at 8th day after operation to 0.4-0.7×103/mm3, and petechia and ecchymosis were noticed in skin. The patient was cut off the administration of LMOX, and he was recovered platelet count 2 days after giving predonin.
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