Abstract
The strains studied here were isolated at the institutes where clinical tests of new antimicrobial agents from September, 1989 to June, 1991 was conducted by multi centric isolation method.
The total number of the strains was 1024; among them 563 were aerobic, Gram positive strains (55.0 %) . Including anaerobic strains, the total number of Gram positive strains was 813 (78.4 %) . Measurement of minimum inhibitory concentration (MIC) was carried out by the standard method of the Japan Society of Chemotherapy.
Although the susceptibility of ampicillin remains as low as before, among those continuously used, there are some which show comparatively high MIC's. It seemed that ampicillin has come to be influenced by some resistance.
The susceptibilities of ester-type cephems, cefteram pivoxil (cefteram), cefuroxime axetil (cefuroxime) and cefpodoxime proxetil (cefpodoxme) are all excellent. Cefdinir (non-ester-type) also has excellent susceptibility.
