Abstract
In the present study, new oral cephems, cefpodoxime proxetil (CPDX-PR), cefteram pivoxil (CFTM-PI), cefuroxime axetil (CXM-AX), cefetamet pivoxil (CEMT-PI) and cefditoren pivoxil (CDTR-PI) were administered orally to five healthy male volunteers after meal with crossover tests. Afterwards blood concentrations of the drugs were measured by bioassay. A pharmacokinetic study was performed using one compartment model.