Abstract
Odontogenic karatocysts tend to recur after surgery. Voorsmit first used Carnoy's solution to prevent the recurrence of keratocysts, but few experimental studies have assessed the basic properties of this solution. Therefore, the penetration depth of Carnoy's solution in the labial gingiva of the mandible of Sprague-Dawley rats was measured after staining with Berlin blue stain. The resules of this in vitro experiment suggested that Carnoy's solution penetrates below the epithelium of odontogenic keratocysts by soaking in it from 1 to 3 minutes.