ORAL THERAPEUTICS AND PHARMACOLOGY
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
Clinical Evaluation of Sai-boku-to (kanpo medicine) for glossodynia
TAKEYA YAMADAKAZUHISA BESSHOKENICHIRO MURAKAMISHINSUKE HORITADAHIKO IIZUKANATSUKI SEGAMI
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1998 Volume 17 Issue 1 Pages 18-22

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Abstract
This study was conducted to asses the clinial efficacy of Sai-boku-to (Kanpo) in comparison to minor tranquilizer with vitamin B complex medication for the treatment of glossodynia.
Either Sai-boku-to (7.5g per day) of minor tranquilizer (Diazepam) 6mg per day with vitamine B complex medication for three months was P. O. administered to 104 cases. The clinical examination was carried out in order to evaluate the subjective symptoms such as pain, heat sensation, and unpleasent feeling in comcomitant treatment of glossodynia.
After three-month administration the success rates were 75.8 %, 87.1 %, and 88.7 % in the Sai-boku-to medication group and 73.8 %, 71.4 %, 69.0 % in the minor tranquilizer medication group. The Sai-boku-to medication group was significantry superior to the minor tranquilizer medication group. The side effect of the sleepiness was found in 13 cases in the minor tranquilizer medication group. On the contrary, a mild signs and symptoms of digestive discomfort was noted in three cases in the Sai-boku-to medication group.
These results suggested that Sai-boku-to was a clinically useful drug for the treatment of glossodvnia.
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