Abstract
The relation between recurrent chronic osteomyelitis and IgG subclass deficiency has been suggested. In the present study, IgG subclasses concentrations in 7 patients with chronic mandibular osteomyelitis were investigated. Two patients with chronic therapy resistant osteomyelitis had a low level of the IgG3 subclass. Impaired host defense response could be a possible factor inducing chronic osteomyelitis in the mandihle.
