抄録
The amount and kinds of injections for carcinoma purchased between Apr. 1, 1995 and Mar. 31 1996, at 10 national university dental hospitals in Japan were investigated.The most commonly used anticancer agents were the platinum complexes. Although three different platinum comlex agents were used, cisplatin was the most commonly used agent. The second commonly used agent was Picibanil®; four different potency preparations (0.1-5KE) were available on the market. The most frequently used Picibanil® agent was 1KE, which constituted 81 % of these prescriptions. The antimetabolites agents were the third most commonly purchased anticancer preparations. Tegaful and 5-fluorouracil were the two approved agents of this class used by dental hospitals for cancer of the head and neck. Antibiotics were the fourth most commonly used class of anticancer agents. Peplomycin sulfate was the most frequently used antibiotic (50 %), bleomycin was second (27 %), and mitomycin C was third (20%) in this class of agents.
Other anticancer agents used in the field of oral surgery were methotrexsate, dacarbazine doxisorubicin hydrochloride, teceleukin, etc.
In our hospitals, the appropriateness of selected anticancer agents for injections was higher than had been anticipated.
