Abstract
The rate of transient bacteremia at the time of tooth extraction using 300mg of cefditoren pivoxil (CDTR), an oral antimicrobial agent, on 56 patients needing tooth extraction was examined. As a result of the examination, 18 patients (32.1%) were positive and 23 strains were isolated. Fourteen strains out of 23 isolates were Streptococcus. The MICs of CDTR were ≤0.025 to>100μg/mL. The serum concentrations of CDTR were also measured, and varied from ≤0.025 to 5.5μg/mL.
The incidence of transient bacteremia using CDTR was the next lowest after amoxicillin (23.3%) among other oral antimicrobial agents with similar examination.
