Antibacterial effect of Taisoal^® against oral bacterial flora

Abstract

The effect of Taisoal contained 0.5% Irgasan DP300 on bacterial flora in saliva and minimal inhibitory concentration against Candida species were examined.
Growth of bacteria in saliva (10³-10⁵ CFU/ml) was absolutely inhibited by treatment with 8% for 10 minutes and 12%, 2.5 minutes, however 99.9% of bacteria except Streptococcus mitior and Bacillus sterothermophilus were inhibited by treatment with 4% for 10 minutes.
With 2% of Taisoal, Candida species in saliva were inhibited.
The minimal inhibitory concentration against 8 species, 75 strains of Candida was less than 0.1%.