Comparative clinical study of Ofloxacin (OFLX) with Talampicillin hydrochloride (TAPC) in the treatment of oral infections

JIRO SASAKI; MASATAKA UEMATSU; HARUO SAKAMOTO; HIROSHI TAKAI; KATSUYOSHI IKESHIMA; HIROJI OZAKI; KAZUO SHIIKI; NOBUO YAMANE; TOSHIHIRO YOSHIDA; TAKEFUMI MORIHANA; AKIHIRO KANEKO; HIDEKI OGIUCHI; YOSHIKUNI SANGU; TAKAHO KUWAZAWA; YASUNOBU UCHIDA; YOSHIHIRO NARITA; SUMIO HOSHIYAMA; YOSHIO HISANO; TAZUKO SATOH; ATSUSHI NOMURA; KEN-ICHI MICHI; HIROMICHI AKIZUKI; KATSUNORI ISHIBASHI; KOHICHI ASADA; KAZUNORI OHTSUBO; TAKANORI HATTORI; NORIAKI IKEDA; SUSUMU IIDA; TADASHI YAMAMOTO; HIROSHI FUJIWARA; KEIKICHI SHIMADA; KOHICHI NAKANISHI; TAMOTSU OKUSHA; KOHICHI DEGUCHI; NOBUYA OGAWA

doi:10.11263/jsotp1982.6.45

JIRO SASAKI, MASATAKA UEMATSU, HARUO SAKAMOTO, HIROSHI TAKAI, KATSUYOSHI IKESHIMA, HIROJI OZAKI, KAZUO SHIIKI, NOBUO YAMANE, TOSHIHIRO YOSHIDA, TAKEFUMI MORIHANA, AKIHIRO KANEKO, HIDEKI OGIUCHI, YOSHIKUNI SANGU, TAKAHO KUWAZAWA, YASUNOBU UCHIDA, YOSHIHIRO NARITA, SUMIO HOSHIYAMA, YOSHIO HISANO, TAZUKO SATOH, ATSUSHI NOMURA, KEN-ICHI MICHI, HIROMICHI AKIZUKI, KATSUNORI ISHIBASHI, KOHICHI ASADA, KAZUNORI OHTSUBO, TAKANORI HATTORI, NORIAKI IKEDA, SUSUMU IIDA, TADASHI YAMAMOTO, HIROSHI FUJIWARA, KEIKICHI SHIMADA, KOHICHI NAKANISHI, TAMOTSU OKUSHA, KOHICHI DEGUCHI, NOBUYA OGAWA

Author information

JIRO SASAKI
Department of Oral Surgery, School of Medicine, Tokai University
MASATAKA UEMATSU
Department of Oral Surgery, School of Medicine, Tokai University
HARUO SAKAMOTO
Department of Oral Surgery, School of Medicine, Tokai University
HIROSHI TAKAI
First Department of Oro-Maxillo-Facial Surgery, Tohoku Dental University
KATSUYOSHI IKESHIMA
First Department of Oro-Maxillo-Facial Surgery, Tohoku Dental University
HIROJI OZAKI
First Department of Oro-Maxillo-Facial Surgery, Tohoku Dental University
KAZUO SHIIKI
Department of Dentistry and Oral Surgery, Iwaki Kyoritsu General Hospital
NOBUO YAMANE
Department of Dentistry and Oral Surgery, Iwaki Kyoritsu General Hospital
TOSHIHIRO YOSHIDA
Department of Dentistry and Oral Surgery, Iwaki Kyoritsu General Hospital
TAKEFUMI MORIHANA
Department of Dentistry and Oral Surgery, Ashikaga Sekijuji Hospital
AKIHIRO KANEKO
Department of Dentistry and Oral Surgery, Ashikaga Sekijuji Hospital
HIDEKI OGIUCHI
Department of Oral Surgery, Tokyo Women's Medical College
YOSHIKUNI SANGU
Department of Oral Surgery, Tokyo Women's Medical College
TAKAHO KUWAZAWA
Department of Oral Surgery, Tokyo Women's Medical College
YASUNOBU UCHIDA
Department of Oral Surgery, Tokyo Medical College
YOSHIHIRO NARITA
Department of Oral Surgery, Tokyo Medical College
SUMIO HOSHIYAMA
Department of Oral Surgery, Tokyo Medical College
YOSHIO HISANO
The Nippon Dental University, School of Dentistry at Tokyo, Department of Oral and Maxillofacial Surgery I
TAZUKO SATOH
The Nippon Dental University, School of Dentistry at Tokyo, Department of Oral and Maxillofacial Surgery I
ATSUSHI NOMURA
The Nippon Dental University, School of Dentistry at Tokyo, Department of Oral and Maxillofacial Surgery I
KEN-ICHI MICHI
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University
HIROMICHI AKIZUKI
First Department of Oral and Maxillofacial Surgery, School of Dentistry, Showa University
KATSUNORI ISHIBASHI
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
KOHICHI ASADA
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
KAZUNORI OHTSUBO
Second Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University
TAKANORI HATTORI
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
NORIAKI IKEDA
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
SUSUMU IIDA
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University
TADASHI YAMAMOTO
Department of Dental and Oral Surgery, Toyohashi Municipal Hospital
HIROSHI FUJIWARA
Department of Dental and Oral Surgery, Toyohashi Municipal Hospital
KEIKICHI SHIMADA
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
KOHICHI NAKANISHI
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
TAMOTSU OKUSHA
Department of Oral and Maxillofacial Surgery, School of Medicine, Kobe University
KOHICHI DEGUCHI
Laboratory Section, Tokyo Clinical Research Center
NOBUYA OGAWA
Department of Pharmacology, Ehime University, School of Medicine

Keywords: Ofloxacin (OFLX), Talampicillin hydrochloride (TAPC), Oral infection, Double-blind comparative study

JOURNAL FREE ACCESS

1987 Volume 6 Issue 1 Pages 45-61

DOI https://doi.org/10.11263/jsotp1982.6.45

Details

Abstract

The clinical effects of three kinds of new type macrolide antibiotics were examined in 86 cases of acute oral and maxillary infection, and the following results were obtained;
1) Clinical efficacy of the three kinds of new type macrolide antibiotics (acetyl-Mide-camycin, Rokitamycin and RU-28965) was 87.0%.
2) Medication term was three days (the shortest) to ten days (the longest) and the mean 4.6 days.
3) Adverse reactions were observed in only 2 patients (3.2%), but thus the drug rushes were not serious and soon disappeared. Abnormal changes in the results of clinical examinations were not found in any cases.

Corresponding author

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