Clinical reevaluation of macrolide antibiotics in the treatment of oral and maxillary infections

Abstract

The clinical effects of three kinds of new type macrolide antibiotics were examined in 86 cases of acute oral and maxillary infection, and the following results were obtained;
1) Clinical efficacy of the three kinds of new type macrolide antibiotics (acetyl-Midecamycin, Rokitamycin and RU-28965) was 87.0%.
2) Medication term was three days (the shortest) to ten days (the longest) and the mean 4.6 days.
3) Adverse reactions were observed in only 2 patients (3.2%), but thus the drug rushes were not serious and soon disappeared. Abnormal changes in the results of clinical examinations were not found in any cases.