Clinical evaluation of SR-318T on postexodontic pain

Abstract

The study was conducted to examine the analgesic efficacy and safety of SR-318T, a sustained-release tablet containing dichlofenac sodium, after tooth extraction, 63 adult patients with postexodontic pain which needed an analgesic drug were each administrated with 2 tablets of (18.75 mg of dichlofenac sodium/1 tablet) .
1. The effective rate was 85.7% according to impressions of patients, and 82.5% in the judgement of the doctor.
2. Side effects reported in 3 of 63 patients (4.8%) ; such as warm feeling, drowsiness and heavy-headed feeling. However, these were slight symptoms and it was considered that there was no relationship with the administrating of SR-318T.
3. In the judgement by our group, the reduction of a pain was 50.8% and the speed was 88.9%, the duration of efficacy was 93.7% over “effective” respectively. The global effective rate was 85.7%. And the utility considering safety was 87.3%.
Concluding results of this study; it was considered that SR-318T is effective and safe for relieving postexdontic pain.