Abstract
The blood concentrations of cefteram were compared by a crossover test in 8 healthy volunteers who were perorally given cefteram pivoxil (CFTM-PI) fasting and after a meal. The results were analysed by pharmacokinetics and moment analysis.
CFTM-PI is advantageous after a meal rather than when fasting, and the administered dosage of 200 mg was superior to the administered dosage of 100 mg.
From the result of pharmacokinetics and moment analysis, it was found that MRT was useful reducing a biological half life as indicated by the results of pharmacokinetics.