Abstract
In order to obtain a longer effective time with same dose of antibacterial agents, by contriving efforts on method of intravenous injection, the blood level of antibacterial agent was compared.
Three method of intravenous injection practically used in clinical study were adopted in the present study. Cephaloridine was three methods of intravenous injection, individually in NZW rabbits. The blood levels of cephaloridine were measured and compared. The blood levels were further subjected to pharmacokinetics and moment analysis to find the superiority or inferiority. The rerults showed that drip infusion (continuous intravenous injection), simultaneously with rapid intravenous injection (group-1) was excellent, drip infusion (continuous intravenous injection) only (group-3) is a little inferior and the two-time rapid intravenous injection (group-2) the worst.
