Abstract
In this study, we have performed two-dimensional simulations of multi-component systems by employing the freeenergy functional F{Φα (r)}. First, we conducted a simulation of a mixture of AB amphiphilic molecules and S solvent to verify the stability of a vesicle structure. In the study, we found the range of the radius R to retain a vesicle structure under certain conditions. Then, we performed a simulation of a mixture of AB amphiphilic molecules, CD amphiphilic molecules, and S solvent to examine phase-separation dynamics on a vesicle membrane. The results showed the difference of phase separation among the radius R and χ parameter (χAC and χBD), enabling us to obtain the χAC, χBD- R phase diagram
