Abstract
Objective: Development of MicroRint has enabled measurement of airway resistance using the interrupter technique, and this device is expected to be useful for asthma management in children. However, there are no published data on airway resistance values measured with it in healthy Japanese children. We developed prediction equations of Rint values based on age, height, and other factors.
Subjects and Methods: Rint measurement was performed before and after inhalation of bronchodilator in children with bronchial asthma who are symptom free for more than two weeks. The prediction equations from height and age was examined based on the values obtained before inhalation in the cases with less than 10% of change.
Results: Of the subjects, 63 met the inclusion criteria. Their median age was 5.3 years, the median height was 109cm. The approximate linear equation y=-0.0529x+0.9552 was obtained from age, while y=-0.0109x+1.8525 was obtained from height. The correlation was slightly higher for the prediction equation obtained from height (coefficient of determination [r2] for these equations were 0.1656 and 0.2242, respectively).
Conclusion: Rint values have been reported to be highly correlated with height, and the results of the present study were similar tendency to them. Further discussion of prediction equations based on Rint values obtained from healthy children is needed.
