Abstract
Food-protein induced gastrointestinal allergy is one of the uncommon diseases in newborn and infant. Recently case reports of these diseases are increasing in Japan. Gastrointestinal symptoms such as vomiting, diarrhea, and bloody stool are common in the onset of this disease. We experienced a case with vomiting and eosinophilic bloody stool developing hypertrophic pyloric stenosis. Histopathological examination was demonstrated that many eosinophils infiltrated with minimal degranulation in hypertrophic pyloric muscle. Allergen specific lymphocyte stimulation test with cow's milk products were elevated. These findings indicated that our case was the food protein-induced gastrointestinal allergy with eosinophilic pyloric stenosis.