2020 Volume 34 Issue 2 Pages 291-302
Background: Systemic corticosteroids are used mainly in the management of children who suffer from very acute asthma attacks. There is a lack of consensus regarding corticosteroid administration.
Objectives: To evaluate the benefit of systemic corticosteroids for hospitalized acute pediatric asthma.
Methods: Randomized controlled trials about systemic corticosteroids compared to placebo and inhaled steroids in hospitalized acute pediatric asthma were identified, and the results of the selected studies were included in a meta-analysis
Results: Ten trials were included. There were no significant differences between groups in the length of stay or pulmonary function. Neither were there any significant differences of duration of oxygen supply or bronchodilators. Children treated with systemic steroids were less likely to prolong symptoms and relapse after discharge.
Conclusion: Systemic corticosteroids are beneficial to pediatric acute asthma attacks. Further studies examining differing doses and durations of corticosteroids will reveal the most effective therapy.
