2020 Volume 34 Issue 2 Pages 303-311
Background: Systemic corticosteroids are used mainly in the management of children suffering from very acute asthma attacks, but we don't know which regimen is most beneficial.
Objectives: To evaluate different doses or durations of oral steroids for pediatric asthma attack by systematic review.
Methods: Randomized controlled trials about different regimen of oral corticosteroids in acute pediatric asthma were identified and the results of the selected studies were included in a meta-analysis.
Results: We have done a screening and included the nine studies. There were no significant differences between groups in hospitalization or prolong symptoms or side effects. It was difficult to analyze the results of the studies because investigators used a variety of doses and durations of steroids. A complete evaluation wasn't possible because the evaluator didn't include data regarding child patients under two years old in the study.
Conclusion: There were no differences of clinical effect with different regimens (types or doses or durations of oral steroids) for pediatric asthma attack.