Abstract
One hundred and thirty nine asthmatic children and twenty non asthmatic children were studied. The acetylcholine and histamine inhalation tests were performed according to the standarized method.
1) Reproducibility of MEFV curve in children was examined. FEV1.0, an index of airway obstruction, was reliable.
2) Over all age a 20% fall in FEV1.0 was adequate to examine the asthma provocation in the inhalation tests.
3) RT-Ach and RT-Hist were correlated with severity.
4) The acetylcholine and histamine tests were clinically useful in asthmatic children.