Abstract
We reported 6 cases of severe atopic dermatitis with hypoalbuminemia. They were infant and all male. In 2 of them serum albumin levels were 1.23g/dl and 1.84g/dl. These 2 infants were given intravenous albumin transfusion therapy. However in the other patients, serum albumin reached to normal levels after skin treatment with steroid ointment. The possible causes for hypoalbuminemia were mainly increasing loss of protein through the skin and partly decreasing protein supply by food intolerance in infants. The risk factors for these severe dermatitis were bacterial skin infections, sensitivity for multiple allergens, and inadequate therapy. We concluded that patients' education and avoidance from these risk factors are important to prevent severe atopic dermatitis with hypoalbuminemia.