Abstract
Recently the relationship between chronic airway inflammation and bronchial responsiveness in asthma has been reported. However, these relationship in childhood asthma is not so recognized. The measurement of exhaled nitric oxide (ENO) is one of the non invasive method, which is assessed airway inflammation. Therefore we evaluated the relationship between the concentration of ENO and bronchial responsiveness. In the group without inhaled steroid treatment, significant correlation were observed between the concentration of ENO and the bronchial responsiveness. Also significant correlation were observed between the concentration of ENO and the maximum %fall in FEV1.0 by bicycle ergometer exercise test. We recognized statistically significant relationship between bronchial hyperresponsiveness and the concentration of ENO.
