Abstract
This article describes a retrospective study assessing the effect of early intervention with inhaled sodium cromoglycate in childhood asthma. The study was performed using the records of 54 severe asthmatic children treated with inhaled sodium cromoglycate for 5years and when asthma was first diagnosed during 0.0 and 11.0 years old. They were divided into the Early Intervention Group (sodium cromoglycate inhalation started within 2 years of the onset of asthma; n=41, male: 37, female: 4, the mean age of the onset of asthma was 1.8±1.4 years) and the Control Group (sodium cromoglycate treatment started more than 2 years after the onset of asthma; n=13, male: 7, female: 6, the mean age of the onset of asthma was 2.2±1.2 years). Early intervention with sodium cromoglycate shows greater improvements over time in clinical scores, treatment scores, asthma scores, severity scores, proportions of patients that required additional treatment with inhaled corticosteroids and number of emergency department visits. Our results suggested the early use of inhaled sodium cromoglycate by a nebulizer might be a treatment with an activity of good long term prognosis of childhood asthma.
