STUDIES ON ERYTHROCYTE CR1 IN PATIENTS WITH ATOPIC DERMATITIS
1989 Volume 3 Issue 2 Pages 111-116
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1989 Volume 3 Issue 2 Pages 111-116
The determination of erythrocyte CR1 in the blood circulation was made using the IAHA method in 69 patients with atopic dermatitis whose ages ranged from two months to 48 years. The following results were obtainded:
1) In patients with atopic dermatitis, there were 21 cases (30%) with negative CR1 activity and thus the frequency was significantly high. On the other hand, in 146 healthy control cases, there were only 12 cases (8%) of negative CR1 activity. Therefore, the number of cases of negative CR1 activity was significantly higher in patients with atopic dermatitis.
2) When such cases were classified by age, it was found that the number of negative cases was higher in newborns of infants in comparison with the controls but that the ratio drew nearer to that in the controls after the age of two to three years.
3) No obvious trend was noted between the negative CR1 activity cases and the positive cases regarding the lesions on the skin, atopy in the air passage and the prognosis.
4) More negative CR1 activity cases were observed in the serum IgE normal group.
5) No definite trend of erythrocyte count, hemoglobin, eosinocyte count, C3, C4 and immunocomplex was necessarily observed between the negative and positive CR1 activity cases.
