THE STUDY OF 0-YEAR ALLERGIC CHILDREN

THE RELATIONSHIP AMONG ALLERGIC SYMPTOMS, IgE RIST TITER AND EOSINOPHILE COUNT

Abstract

We investigated the increase of IgE RIST titer and eosinophile counts in 56 0-year allergic children. (male 31, female 25; wheezy children 11, children with atopic dermatitis 21, wheezy children with atopic dermatitis 21, and other allergic children 2)
We measured IgE RIST titer by using the radioimmunoassay Sephadex method.
We recognized that there were many male children among the wheezy children with atopic dermatitis group, and many female children in the atopic dermatitis group.
There was a strong trace of allergic heredity in the patients. IgE RIST titer in allergic children over 8 months, was higher than that of allergic children under 5 months. But the eosinophile counts of those allergic children did not show such a tendency. This was becouse there were high eosinophile counts for the group containing children under 5 months.
Then we set up the standard level of both examination values.: IgE RIST 30IU/ml: eosinophile count 200/mm³.
By these standard levels, we investigated the 3 groups; the wheezy children group, the atopic dermatitis group, and the wheezy children with atopic dematitis group. The high average ratio over the standard level was as follows: atopic dermatitis group>wheezy children with atopic dermatitis group>wheezy children group.