Abstract
The aim of the present study was to observe the effect of the active vitamin D3 supplement on the mandibular alveolar bone. Fifity weaned Wistar male rats aged 3 weeks were used. The rats were fed on a low Ca diet or a Ca deficient diet during first three weeks, with their food then changing to a standard diet or a standard diet plus active vitamin D3 during the latter three weeks respectively. The mandibular alveolar bones were observed using Ca, P microanalysis and bone mineral mass. The results were as follows: 1)The observation of Ca, P microanalysis revealed that the groups with the standard diet plus active vitamin D3 showed significantly higher values than the groups with the pairfed standard diet. The control group showed the best result among all of the groups based on Ca, P microanalysis. The results of ratio of the Ca/P of the microanalysis showed that the control group was higher than the group with the low Ca + standard diet plus active vitamin D3 which was higher than the group with the low Ca + standard diet which was higher than the group with the Ca deficient +standard diet plus active vitamin D3 and which was higher than the group with the Ca deficient +standard diet.2)The control group showed the best result among all of the groups on bone mineral mass. The value of standard diet plus vitamin D3 group was significantly higher than that of the group with a pair-fed standard diet among the low Ca diet groups; but those values did not showed a significant difference between the groups with the pair-fed among Ca deficient diet groups although the value of the group with the standard diet plus active vitamin D3 group was higher than that of the group with the standard diet group.
