体力科学
Online ISSN : 1881-4751
Print ISSN : 0039-906X
ISSN-L : 0039-906X
資料
ビタミンCが一過性の受動喫煙時の動脈機能に及ぼす影響
東 亜弥子三浦 哉石川 みづき
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2019 年 68 巻 2 号 p. 153-157

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As well as active smoking, passive smoking is associated with a high risk of developing cardiovascular disease. The antioxidant vitamin C may inhibit the unfavorable effects of passive smoking. In this study, we investigated the effects of vitamin C ingestion on changes in the flow-mediated dilatation (FMD) at the brachial artery in patients exposed to transient passive smoking. The study participants included seven healthy adult males who were examined by high-resolution ultrasonography of the brachial artery before and after 15-minute of passive smoking. FMD was used to examine the endothelial function. Randomized crossover controlled trial, measurements were performed on two different days 120-minute after the oral administration of 1000mg of ascorbic acid (VC trial) or a placebo (P trial). Although the FMD values decreased after passive smoking in both trials, the FMD values of the VC trial were higher than those of the P trial, with significant differences between the trials observed immediately and 30-minute after passive smoking. The results of this study suggested that the ingestion of vitamin C may suppress the decrease in the vascular endothelial function caused by transient passive smoking.

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© 2019 一般社団法人日本体力医学会
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