協働筋切除に伴う過負荷が再生時骨格筋の機能的, 形態的特性に及ぼす影響

抄録

The contractile and morphological effects of chronic overload induced by synergist gastrocne mius and soleus ablation were studied in regenerating plantaris muscle of rats after injuries produced by eccentric exercise. Rats were randomly divided into control (C), eccentric exercise (E) synergistic ablation (S) and eccentric exercise+synergistic ablation (ES) groups. At 6 weeks after the experimental treatment, contractile or morphological muscle properties were measured. The maximum tetanic tension of ES group was significantly larger than that of S group (p<0.05), although there was not significant difference between C and E groups. There was not significant difference in contraction time between S group and ES group. While there was not significant difference in mean cross-sectional area of any fiber types between C group and E group, all fiber types of ES group were significantly smaller than that of S group (p<0.05) . It is concluded that the overload on injured muscle by eccentric exercise may restrain muscle hypertrophy.