生薬学雑誌
Online ISSN : 2433-8486
Print ISSN : 1349-9114
天然薬物ノート
Chemical Compounds from the Leaves of Verbascum thapsus and Their Xanthine Oxidase Inhibitory Activity
Minpei KurodaKatsura IwabuchiSaori UsuiNanami AkiyamaYoshihiro Mimaki
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2017 年 71 巻 1 号 p. 49-50

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Phytochemical screening of the MeOH extract of Verbascum thapsus leaves resulted in the isolation of four flavonoids, two flavonolignans, five phenylethanoids, and one monoterpene glucoside. Among the isolated compounds, two flavonolignans, hydnocarpin and hydnocarpin-D, showed potent xanthine oxidase inhibitory activity with IC50 values of 2.89μM and 12.0μM, respectively.

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© 2018 The Japanese Society of Pharmacognosy
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