Palliative Care Research
Online ISSN : 1880-5302
ISSN-L : 1880-5302
Case Report
A Case of Allergy Suspected to Be Caused by Pharmaceutical Additive in Acetaminophen
Satoko HaraguchiYoshiko TakahashiKoki OkuboMisaki NishionoMiki SakakiYusei Haraguchi
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Supplementary material

2019 Volume 14 Issue 3 Pages 197-201

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Abstract

Background: Acetaminophen, an antipyretic analgesic, is one of the main pain relief medications for cancer according to the World Health Organization guidelines. Design: A case report of a 75-year-old woman who had been taking acetaminophen to relieve cancer pain caused by recurrence after surgery for left upper-lobe cancer and multiple bone metastases. Following a formulation change, the participant experienced allergy-like symptoms. Results: After switching to a different formulation, the allergic symptoms disappeared. Conclusion: The results obtained from this case report suggest that pharmaceutical additives in the acetaminophen formulation caused the allergic reaction, and not the acetaminophen itself. The woman’s pain was successfully controlled by changing to a different type of formulation. If allergic reaction symptoms appear after taking acetaminophen, switching to a different formulation of the drug may enable the continued use of acetaminophen to treat the patient’s pain.

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© 2019 by Japanese Society for Palliative Medicine
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