Abstract
Case: Cancer patients without impaired glucose tolerance developed hypoglycemia during the administration of quetiapine. After increasing the amount of the drug, hypoglycemia was developed in the wake of fasting. Discussion: There is a possibility that quetiapine inhibited the hypoglycemic compensatory reactions during starvation. Conclusion: In cancer patients taking quetiapine, it is necessary to observe the onset of symptoms of hypoglycemia as well as hyperglycemia in mind. And blood glucose measurement on a regular basis is desirable.