Genomic global linkage analysis in cyanobacteria

Abstract

Conservation of gene order in different genomes is a measure of genome evolution. Conventional way of such analysis relies on sequence homology of genes within a selected set of genomes, but the increase in evolutionary distance reduces the reliability of orthology. In this study, we used catalogs of homologous genes that conserved in a set of cyanobacterial genomes estimated by the Gclust server ( http://gclust.c.u-tokyo.ac.jp ) . We analyzed the distance relations of homologous genes between genomes. We previously reported a result of comparison of 16 cyanobacteria. In that result, homologous genes formed neighboring series and formed mosaic structure in global scale. In this presentation, we report the advanced result from the enhanced dataset which contains 25 cyanobacterial genomes .