Analysis of CLV3 processing

Abstract

Shoot apical meristem (SAM) contains undifferentiated stem cells, and they divide to produce new tissues. SAM has important roles in shoot development and regulation of SAM is necessary for appropriate shoot formation. It is suggested that CLV3 regulates maintenance and differentiation of stem cells in SAM via receptors like CLV1, CLV2, and SOL2. At first, CLV3 is translated as a 96 amino acid containing peptide. This peptide is processed to be mature 13 amino acid containing CLV3 peptide, but this processing mechanism is still unknown. In order to know the molecular mechanisms of CLV3 peptide processing, we performed genetic and biochemical analyses. Here we will discuss about our recent work about it.