Abstract
In the next generation of structural studies of biological samples, coherent X-ray diffraction microscopy (CXDM) technique will provide a novel tool to visualize non-crystalline biological particles, which are, in principle, unable to be crystallized. For the diffraction patterns recorded using coherent and highly brilliant X-rays, the phase-retrieval algorithm reconstructs the electron density distribution within the samples directly. Toward the utilization of this technique in biological field, we are developing an X-ray diffraction apparatus for micro to sub-micrometer biological samples at cryogenic temperatures. In the talk, I would like to introduce the theoretical background of the image reconstruction from the diffraction patterns and the details of the diffraction apparatus.
