Journal of Japanese Society of Pediatric Radiology
Online ISSN : 2432-4388
Print ISSN : 0918-8487
ISSN-L : 0918-8487
Case Report
Two neonates with characteristic MRI findings of neurocutaneous melanosis
Ryo Aoki Hiroko HaraYosuke YamadaShio TsurutaHisaya Hasegawa
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2019 Volume 35 Issue 2 Pages 143-147

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Abstract

Neurocutaneous melanosis (NCM) is a rare congenital disease consisting of development of congenital giant melanocytic nevi and CNS melanocytosis. We present two neonates who had giant congenital nevi and multiple smaller satellite melanocytic nevi on the scalp and extremities, with brain MRI findings characteristic of NCM. In both neonates, MRI demonstrated multiple brain parenchymal foci of T1 hyperintensity and T2 hypointensity, signal characteristics of melanin with the T1, and T2 shortening effects. These foci were seen in the amygdalae, brain stem, and cerebellum. In one neonate, dilatation of the ventricular system and subarachnoid space was identified, representing communicating hydrocephalus. These intracranial findings are characteristic of NCM. No obvious leptomeningeal contrast enhancement was demonstrated. MRI can provide useful information for the diagnosis and follow up of NCM.

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© 2019 Japanese Society of Pediatric Radiology
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