Hypertension Research in Pregnancy
Online ISSN : 2187-9931
Print ISSN : 2187-5987
ISSN-L : 2187-5987
Original Article
Early detection of thrombosis after cesarean section using changes in D-dimer levels
Yuko MatsumuraYuka Yamamoto Iwaho KikuchiNanase TakahashiYuko MatsudaTomomi SaitoTakashi YorifujiShintaro MakinoAtsuo ItakuraSatoru Takeda
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2014 年 2 巻 1 号 p. 26-29

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Aim: To identify important factors that can be used to predict the presence of venous thromboembolism (VTE) or pulmonary embolism (PE) after cesarean section.
Methods: This retrospective study was conducted at Juntendo University Hospital from January to December in 2012. A total of 313 patients who underwent cesarean section were included. Complete blood count, biochemistry parameters, and parameters of coagulation-fibrinolysis, such as D-dimer levels, were examined on the day before cesarean section and on postoperative days 1, 3, and 5.
Results: Six cases of VTE and/or PE were identified. We designed an equation that incorporates changes in D-dimer levels for predicting the presence of thrombosis, as follows: y=(D1 D-dimer)×1.263−(D3 D-dimer)×1.741+(D3/D1 D-dimer)×6.42+(D5 D-dimer)×4.029−53.248. When the resulting value is > 20, the patient is considered likely to have thrombosis.
Conclusions: This study showed that rate of change in D-dimer levels from postoperative day 1 to day 3, and D-dimer level itself on postoperative day 5, are important factors for predicting the presence of VTE or PE.
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© 2014 by Japan Society for the Study of Hypertension in Pregnancy
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