抄録
Aim: To identify important factors that can be used to predict the presence of venous thromboembolism (VTE) or pulmonary embolism (PE) after cesarean section.
Methods: This retrospective study was conducted at Juntendo University Hospital from January to December in 2012. A total of 313 patients who underwent cesarean section were included. Complete blood count, biochemistry parameters, and parameters of coagulation-fibrinolysis, such as D-dimer levels, were examined on the day before cesarean section and on postoperative days 1, 3, and 5.
Results: Six cases of VTE and/or PE were identified. We designed an equation that incorporates changes in D-dimer levels for predicting the presence of thrombosis, as follows: y=(D1 D-dimer)×1.263−(D3 D-dimer)×1.741+(D3/D1 D-dimer)×6.42+(D5 D-dimer)×4.029−53.248. When the resulting value is > 20, the patient is considered likely to have thrombosis.
Conclusions: This study showed that rate of change in D-dimer levels from postoperative day 1 to day 3, and D-dimer level itself on postoperative day 5, are important factors for predicting the presence of VTE or PE.