Abstract
The relationship between the skin irilalion caused by skin barriers and tack characteristics of skin barriers were analysed. Skin irritation rate by skin barrier was the higher in CMC type barrier,while lower in mixed and karaya type. As to tack characteritics,CMC and mixed type showed strong adhesiveness,on the contrary karaya type showed poor adhesiveness.
These results sugested that skin barrier with high adhesiveness might cause mechanical skin injury on peristomal skin. And it is estimated that the repair of this injury could be promoted by some ingredient of skin barrier,especially Karaya Gum. Karaya has shortcomming in physical property as skin barrier,although it has excellent skin protecting function as well as excellent properly for dressing.
It was emphasized that the development of the most desirable skin barrier in the future could be attained by analysing skin protecting property of Karaya Gum.