Abstract
In our aging society, surgical treatment of wounds in patients with various coexisting illnesses is common. Treatment of such wounds takes a long time, and in several cases MRSA is detected by culture, even if there are no symptoms of infection. Consensus has not been obtained regarding the selection of antimicrobial agents used in operations for wounds that have not been tested for MRSA infection. We operated on 13 cases that did not have any symptoms of infection, even though MRSA was detected after the operation. We then examined the presence of surgical site infection by using first-generation cefem as a preventive antimicrobial agent as well as normal clean operation techniques. As a result, 12 cases fully recovered without MRSA infection after the operation. One case had necrosis of the flap and MRSA infection after the operation. However, we thought that the infection resulted from technical errors. Therefore, we propose that selection of a prophylactic antibiotic for surgery of MRSA-colonized wounds is sufficient, by using the usual preventive antimicrobial agents and clean operation techniques.