抄録
Objective: To scrutinize the status of lung transplantation in Japan, the Japanese Society of Lung and Heart-Lung Transplantation started to collect and present registry data from 2005. This is the 9th official registry report of Japanese lung transplantation.
Design and Methods: The data of cadaveric lung transplantation and living-donor lobar transplantation performed by the end of 2012 were registered in the database and analyzed with respect to the number of transplants, recipient-survival rates, recipient functional and working statuses, and causes of death after transplantations. Survival rates were calculated by the Kaplan-Meier method.
Results: A total of 157 cadaveric lung transplantations (87single and 70 bilateral), 125 living-donor lobar transplantations and 1 heart-lung transplantation procedures were performed by the end of 2012. Five-year and 10-year survival rates of cadaveric lung transplantations were 73.5% and61.4%, which were superior to those in the International Registry (52.6% and 30.3%). Five-year and 10-year survival rates of living-donor lobar transplantations were excellent at 73.4% and67.6%. The functional status of more than 85% of recipients was restored to Hugh-Jones I or II after transplantations. Infection was the leading cause of death after lung transplantation. Primary graft dysfunction accounted for 27% of the causes of death after cadaveric lung transplantation.
Conclusion: The results of Japanese lung transplantations are so far satisfactory. Efforts must be made, however, to overcome early deaths resulting from primary graft dysfunctions. The modified Japanese transplantation law has been enforced since July 2010, and an increase in the number of cadaveric organ transplantations has been achieved. The Japanese Society of Lung and Heart-Lung Transplantation will continue to present annual reports of Japanese lung transplantations.
