移植における免疫制御の未来動向

抄録

Transplantation has been developed based on the progress of immunosuppression. During the past half-century, various excellent immunosuppressants have been developed. Furthermore, the induction of immunological tolerance has been investigated to improve the outcome, and it has already been applied clinically. Turning our attention to the future, an age of cellular transplantation using pluripotent stem cells would be realistic. Even in this age, when other-derived pluripotent stem cells as the source of transplantation are used, the idea of immune regulation is important. The investigation of immune regulation using pluripotent stem cells has already been started.