2016 年 51 巻 4-5 号 p. 347-354
Twenty-five years have passed since the liver transplantation program for children started in Japan. Numerous advances in pre- and posttransplant management and surgical techniques have improved the outcome. The Japanese Liver Transplantation Society have registered and followed all graft survivals since the 1989 start of the program. The results have been reported for 2224 cases up to December 2010. The current 20-year survival rate in children was at 79.6 %. Although short-term outcomes have become satisfactory, various issues faced by the long-term survivors have emerged. Here we described each complication associated with graft function, especially focusing on surgical and immunological factors.
