2019 Volume 54 Issue 2-3 Pages 145-149
【Objective】 Few studies have investigated the incidence of abnormalities in electroencephalography (EEG) in pediatric renal transplant patients. The aim of this study was to evaluate EEG before transplantation and investigate the incidence of seizures following transplantation.
【Design】 case control study.
【Methods】 We evaluated the EEG of 235 patient (average age 10.0±5.8 years old) before kidney transplantation.
The results were classified into three groups according to EEG: Seizures group, who had a history of seizures; Abnormal EEG group, who had abnormal EEG before transplantation with no history of seizure; and Normal group, who had normal EEG with no history of seizures. We compared the patient background, frequency of perioperative seizures and reversible leukoencephalopathy (PRES) among the three groups. The Abnormal EEG group were administered sodium valproate prophylactically to prevent postoperative seizures.
【Results】 According to this study, 235 patients were classified into the Seizures group 28 (11.9%), abnormal EEG group 44 (18.7%), and normal group 163 (69.4%). In the Abnormal EEG grope, the proportion of patients under 12 years old was high (p=0.037). Eighteen (7.6%) of 235 patients were complicated by seizures. The incidence of PRES was not different among the three groups (p=0.970). Seventy-five-point-nine percent of the Abnormal EEG group patients improved their EEG after transplantation.
【Conclusion】 Asymptomatic electroencephalogram abnormalities were found in 18.7% of children before kidney transplantation. Three quarters of asymptomatic electroencephalogram abnormalities improved after transplantation. There were no differences in the incidence of PRES among the three groups.
