2023 年 58 巻 4 号 p. 313-317
Japan is experiencing a super-aging society unlike any other in the world. More than half of the living donor kidney transplants carried out in Japan in 2021 were from donors over 60 years old. Many reports indicate that there is no difference in short-term graft survival rates between elderly and young donors. GFR declines with age, but the rate of decline is relatively slow in elderly Japanese people. When evaluating renal function in elderly patients, it is important to note that the discrepancy between serum creatinine levels and GFR is larger than in younger patients. Elderly people may have various comorbidities in addition to age-related decline in renal function, so multidisciplinary evaluation is necessary to determine donor eligibility. After kidney donation, it is necessary to monitor GFR, blood pressure, weight, and presence of proteinuria, as well as promote a healthy lifestyle such as exercise, diet, and smoking cessation, as well as cancer screening and cognitive function evaluation.
