Abstract
Not many studies have been done in patients with hypertensive intracerebral hemorrhage (HIH) to evaluate their regional cerebral blood flow (rCBF). Any previous studies about rCBF in patients with HIH did not say the relationship between the change of rCBF and motor function.
Our study was performed in patients with HIH during resting state and investigated the correlation between mean cerebral blood flow (MCBF) and hematoma volume, duration from the attack, motor function, findings of CT scan. rCBF was measured in 50 patients with putaminal hemorrhage by the133Xe intracarotid injection method.
The results were as follows :
1) The averages of MCBF in each duration within one year showed similar values, averaged about 30ml/100 g/min..
There was, however, a significant difference between the averages of MCBF within one year and that of over one year.
2) There was the close correlation between hematoma volume and MCBF within 3 months from the attack. Most of the cases having had the hematoma over 100 ml showed a relatively low value around 30 ml/100 g/min..
3) Most of cases continued low flow value for a long term, but which was independent on hematoma volume. A few cases with small hematoma revealed a good recovery of MCBF in short time. This findings was not always associated with the recovery of motor function.
4) There was a good relationship between the degree of motor disturbance and reduction of MCBF. The group with severe motor disturbance (Ueda's stages I, II and III) showed less value than 30ml/100 g/min..
5) The cases with a compression against internal capsule on CT scan showed various courses of recovery of MCBF and good recovery of motor function. While, the cases with destruction of internal capsule on CT scan showed less value at second investigation than at the first. However, there is no correlation between the recovery of motor function and that of MCBF in two groups.
