2006 Volume 56 Issue 1 Pages 35-40
The replication of eukaryotic positive-strand RNA virus genomes occurs in membrane-bound replication complexes. Currently, little is known about the process of replication complex formation and the molecular structure of the replication complexes. We are trying to understand how eukaryotic positive-strand RNA viruses replicate using tobamoviruses as models. Here, I describe our approaches to this end.