Abstract
Viroids are autonomously replicating, small single-stranded circular RNA pathogens that cause diseases in infected, susceptible plants. They are non-coding RNA replicon which replicate depending on host transcriptional machinery and develop disease symptoms through interactions with cellular components of the host. The small size and unique molecular structure of viroid RNA makes them an attractive system to analyze molecular features responsible for pathogenesis, RNA transport, or molecular evolution and adaptation to specific host species. Here we show the latest progress in viroid research on new disease epidemics, molecular evolution and host adaptation, and pathogenesis in relation to viroid-induced RNA silencing.
