1973 Volume 23 Issue 1 Pages 36-46
Virologic and serologic studies were conducted on 23 cases of infectious mononuclesis-like illness in children. Of these cases, five were suspected to have been caused by cytomegalovirus six by EB virus. two by adenovirus, and two by cytomegalovirus or EB virus. The other 8 cases were induced by unknown etiology. The five cases caused by cytomegalovirus were below one year old, and displayed hepatosplenomegaly and liver dysfunction. The six cases caused by EB virus were all beyond one year old, and showed pharyngitis and lymphadenopathy.
These differences in clinical manifestations between the two viruses were coincident with those observed in infectious mononucleosis or cytomegalovirus-mononucleosis in American and European adults. Adenovirus and Toxoplasma were also suspected to be etiologic agents of infectious mononucleosis or mononucleosis-like illness.
