1959 Volume 9 Issue 2 Pages 152-156
The nature of ectromelia virus inactivated photodynamically was examined using the system of the virus-Ehrlich ascites cells.
1) The ectromelia virus is very sensitive to the photodynamic action of methylen blue.
2) The virus which has already entered the cells becomes resistant to the photodynamic action.
3) The inactivated virus has no interfering property.
4) The inactivated virus retains its immunogenical property.
5) The formation of inclusion bodies and the development of the inclusion bodies were suppressed in the immunized mouse even when the infection had already progressed for several hours in the normal mouse.