Abstract
This study aimed to evaluate clinical sign of digoxin toxicosis in chronic heart failure dogs administered digoxin. Fourteen dogs with digoxin toxicosis were evaluated in terms of there body temperature, the weight, digestive organ symptom, change of kidney function before digoxin prescription and during appearance of toxicosis. The clinical signs of digoxine toxicosis increased with serum digoxin concentration≥2.0 ng/ml. The body temperature decreased at digoxin intoxication significantly. Creatinine and BUN rose in proportion to increase of serum digoxin level, and digestive symptom (anorexia, vomiting and comparison of diarrhea) developed. These results suggest that the evaluation of body temperature, change of body weight, digestive symptom, renal function (creatinine and BUN) as well as the measurement of serum digoxin level may be useful for diagnosis of the severity in digoxin intoxication and one of a guideline of informed consent for a side effect.
